Formation of Biotinylated Alkylthiolate Self-Assembled Monolayers on Gold
نویسندگان
چکیده
The formation of mixed self-assembled monolayers (SAMs) from novel biotinylated alkylthiols (BAT) and diluent triethyleneglycol (TEG) alkylthiols on gold has been accomplished using aqueous solvents. We compare the effects of aqueous and ethanolic solvents on the binding performance of mixed SAMs and the integrity of monolayers formed. We use cyclic voltammetry (CV) and fluorescence microscopy to characterize the films. Comparison of fluorescence data between solution mixtures of alkylthiols in various concentrations of ethanol and water solvent indicates that functional SAMs may be formed at ethanolic solvent compositions as low as 2% in water. In addition, CV data indicate that SAMs adsorbed from aqueous solution form faster and have fewer defects than those formed using ethanol.
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